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In the SURPASS-2 trial for type 2 diabetes, gastrointestinal adverse events showed a dose-dependent relationship, with higher doses (10 mg and 15 mg) associated with increased frequency of digestive symptoms compared to lower doses (5 mg)
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The most common side effects of GLP-1 medications include nausea, constipation, diarrhea, and fatigue, especially during the first few weeks as your body adjusts